Drug-induced liver injury(DILI)is a leading reason for preclinical safety attrition and post-market drug withdrawals.Dru......

Mitochondria are major sources of cellular energy and reactive oxygen species (ROS), playing fundamental roles in regula......

Aim: In recent years, marketed drugs withdrawn and termination of new drug study in pre-clinical/clinical stage due to m......

Objectives To study troglitazonE-induced liver mitochondrial toxicity in HepaRG cells and explore its possible mechanism......